Skin rejuvenation using cosmetic products containing growth factors, cytokines, and matrikines: a review of the literature

Skin rejuvenation using cosmetic products containing growth factors, cytokines, and matrikines: a review of the literature

Blog Article

Caroline Aldag,1,* Diana Nogueira Teixeira,1,* Phillip S Leventhal2 1Merz Pharmaceuticals GmbH, Frankfurt am Main, Germany; 24Clinics, Paris, France *These authors contributed equally to this work Abstract: Skin aging is primarily Solid spoon due to alterations in the dermal extracellular matrix, especially a decrease in collagen I content, fragmentation of collagen fibrils, and accumulation of amorphous elastin material, also known as elastosis.Growth factors and cytokines are included in several cosmetic products intended for skin rejuvenation because of their ability to promote collagen synthesis.Matrikines and matrikine-like peptides offer the advantage of growth factor-like activities but better skin penetration due to their much smaller molecular size.In this review, we summarize Grinders the commercially available products containing growth factors, cytokines, and matrikines for which there is evidence that they promote skin rejuvenation.

Keywords: cosmetics, skin, aging, growth factor, cytokine, matrikine.